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Pediatric Radiology

Erschienen in:

04.03.2024 | Commentary

Using MRI derived observed to expected total lung volume to predict lethality in fetal skeletal dysplasia

verfasst von: Dorothy I. Bulas, Jamie L. Fraser, Kate Cilli

Erschienen in: Pediatric Radiology | Ausgabe 5/2024

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Excerpt

In their recent article in Pediatric Radiology, Mehollin-Ray and colleagues report their experience in two large referral centers assessing fetal MRI lung volumes as an outcome variable in fetuses with skeletal dysplasia [1]. An observed to expected total lung volume (O/E-TLV) <0.49 was a significant risk factor with a sensitivity of 0.63 and specificity of 0.93. An O/E TLV of <0.38 had a 1.0 specificity for lethality. Companion ultrasounds confirmed that a femur length to abdominal circumference (FL/AC) ratio of <0.129 was also a strong predictor of poor outcome. When a skeletal dysplasia is not clearly diagnosed, total lung volume MR measures may help provide additional data regarding pulmonary hypoplasia, useful when counseling families, and planning deliveries. …

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Titel: Using MRI derived observed to expected total lung volume to predict lethality in fetal skeletal dysplasia
verfasst von: Dorothy I. Bulas
Jamie L. Fraser
Kate Cilli
Publikationsdatum: 04.03.2024
Verlag: Springer Berlin Heidelberg
Erschienen in: Pediatric Radiology / Ausgabe 5/2024
Print ISSN: 0301-0449
Elektronische ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-024-05893-w

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