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Head and Neck Pathology

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16.03.2023 | Special Issue: Top Ten Head and Neck Differentials

Top 10 Significant Spindled Head and Neck Lesions to Scrutinze

verfasst von: Aaron M. Udager

Erschienen in: Head and Neck Pathology | Ausgabe 1/2023

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Abstract

Background

Spindled lesions are a challenging area in head and neck pathology. This is particularly true in the sinonasal tract, where several uncommon entities with both unique and overlapping morphologic, immunophenotypic, and/or molecular features can occur.

Methods

Review.

Results

The clinicopathologic characteristics of biphenotypic sinonasal sarcoma and nine important differential diagnostic considerations with one or more overlapping feature are summarized to establish a practical framework for approaching spindled lesions of the sinonasal tract.

Conclusion

Morphologic evaluation is central to the work up of sinonasal spindle cell lesions–in particular, cellular morphology, tumor architecture and growth pattern, and the presence of admixed epithelial elements – however, focused immunohistochemical analysis of neural, myogenic, rhabdomyoblastic, epithelial, and/or melanocytic marker expression and/or ancillary tests for tumor-specific molecular alterations may be necessary for definitive diagnosis.

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Titel: Top 10 Significant Spindled Head and Neck Lesions to Scrutinze
verfasst von: Aaron M. Udager
Publikationsdatum: 16.03.2023
Verlag: Springer US
Erschienen in: Head and Neck Pathology / Ausgabe 1/2023
Elektronische ISSN: 1936-0568
DOI: https://doi.org/10.1007/s12105-023-01535-z

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Top 10 Significant Spindled Head and Neck Lesions to Scrutinze

Abstract

Background

Methods

Results

Conclusion

Neu im Fachgebiet Pathologie

Assistierter Suizid durch Infusion von Thiopental

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Abstract

Background

Methods

Results

Conclusion

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