Skip to main content
Erschienen in: Clinical Neuroradiology 4/2016

09.11.2016 | Neuroradiologie | Clinical Case

Freiburg Neuropathology Case Conference

A Pituitary Mass Lesion

verfasst von: C. A. Taschner, R. Sankowski, J. M. Shah, H. Urbach, R. Hartmann, M. Prinz

Erschienen in: Clinical Neuroradiology | Ausgabe 4/2016

Einloggen, um Zugang zu erhalten

Excerpt

A 41-year-old woman presented with a history of amenorrhea for 13 years, which was treated with a dopamine antagonist. Magnetic resonance imaging (MRI) performed 3 years earlier revealed a pituitary mass (not shown). Although the initial MRI already showed a compression of the optic chiasm, no neurosurgical consultation was arranged, presumably because the visual examination was normal. The current MRI (Figs. 1 and 2) showed an enlargement of the intrasellar mass. Her visual examination showed a slight decrease of visual acuity and a new bitemporal hemianopia. An endocrinological examination showed a slightly increased serum prolactin level, whereas levels of all other pituitary hormones were within reference ranges.
Literatur
2.
Zurück zum Zitat Thorner MO, Vance ML, Laws ER Jr, Horvath E, Kovacs K. The anterior pituitary. In: Wilson JD, Foster DW, Kronenberg HM, Larsen PR, editors. Williams textbook of endocrinology. Philadelphia: WB Saunders; 1998. pp. 249–340. Thorner MO, Vance ML, Laws ER Jr, Horvath E, Kovacs K. The anterior pituitary. In: Wilson JD, Foster DW, Kronenberg HM, Larsen PR, editors. Williams textbook of endocrinology. Philadelphia: WB Saunders; 1998. pp. 249–340.
3.
Zurück zum Zitat Jagannathan J, Dumont AS, Jane JA Jr. Diagnosis and management of pediatric sellar lesions. Front Horm Res. 2006;34:83–104.CrossRefPubMed Jagannathan J, Dumont AS, Jane JA Jr. Diagnosis and management of pediatric sellar lesions. Front Horm Res. 2006;34:83–104.CrossRefPubMed
4.
Zurück zum Zitat Osborn AG. Osborn’s brain: imaging, pathology, and anatomy, 1st ed. Salt Lake City: Amirsys Pub; 2013. Osborn AG. Osborn’s brain: imaging, pathology, and anatomy, 1st ed. Salt Lake City: Amirsys Pub; 2013.
5.
Zurück zum Zitat Prevedello DM, Jagannathan J, Jane JA Jr, Lopes MB, Laws ER Jr. Relevance of high Ki-67 in pituitary adenomas. Case report and review of the literature. Neurosurg Focus. 2005;19:E11.CrossRefPubMed Prevedello DM, Jagannathan J, Jane JA Jr, Lopes MB, Laws ER Jr. Relevance of high Ki-67 in pituitary adenomas. Case report and review of the literature. Neurosurg Focus. 2005;19:E11.CrossRefPubMed
6.
Zurück zum Zitat Grandidge C, Hall A, Kitchen N. Secreting follicle-stimulating hormone pituitary carcinoma with cervical metastasis. World Neurosurg. 2016;93:490.e13–6.CrossRefPubMed Grandidge C, Hall A, Kitchen N. Secreting follicle-stimulating hormone pituitary carcinoma with cervical metastasis. World Neurosurg. 2016;93:490.e13–6.CrossRefPubMed
7.
Zurück zum Zitat Fuller GN, Scheithauer BW, Roncaroli F, Wesseling P. Spindle cell oncocytoma of the adenohypophysis. In: Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, editors. WHO classification of tumors of the central nervous system. Lyon: IARC Press; 2007. pp. 245–6. Fuller GN, Scheithauer BW, Roncaroli F, Wesseling P. Spindle cell oncocytoma of the adenohypophysis. In: Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, editors. WHO classification of tumors of the central nervous system. Lyon: IARC Press; 2007. pp. 245–6.
8.
Zurück zum Zitat Lee EB, Tihan T, Scheithauer BW, Zhang PJ, Gonatas NK. Thyroid transcription factor 1 expression in sellar tumours: a histogenetic marker? J Neuropathol Exp Neurol. 2009;68(5):482–8.CrossRefPubMed Lee EB, Tihan T, Scheithauer BW, Zhang PJ, Gonatas NK. Thyroid transcription factor 1 expression in sellar tumours: a histogenetic marker? J Neuropathol Exp Neurol. 2009;68(5):482–8.CrossRefPubMed
9.
Zurück zum Zitat Hasiloglu ZI, Ure E, Comunoglu N, Tanriover N, Oz B, Gazioglu N, Mihmanli I. New radiological clues in the diagnosis of spindle cell oncocytoma of the adenohypophysis. Clin Radiol. 2016;71:937.e5–937.e11.CrossRef Hasiloglu ZI, Ure E, Comunoglu N, Tanriover N, Oz B, Gazioglu N, Mihmanli I. New radiological clues in the diagnosis of spindle cell oncocytoma of the adenohypophysis. Clin Radiol. 2016;71:937.e5–937.e11.CrossRef
10.
Zurück zum Zitat Dwyer AJ, Frank JA, Doppman JL, Oldfield EH, Hickey AM, Cutler GB, Loriaux DL, Schiable TF. Pituitary adenomas in patients with Cushing disease: initial experience with Gd-DTPA-enhanced MR imaging. Radiology. 1987;163:421–6.CrossRefPubMed Dwyer AJ, Frank JA, Doppman JL, Oldfield EH, Hickey AM, Cutler GB, Loriaux DL, Schiable TF. Pituitary adenomas in patients with Cushing disease: initial experience with Gd-DTPA-enhanced MR imaging. Radiology. 1987;163:421–6.CrossRefPubMed
11.
Zurück zum Zitat Covington MF, Chin SS, Osborn AG. Pituicytoma, spindle cell oncocytoma, and granular cell tumor: clarification and meta-analysis of the world literature since. AJNR Am J Neuroradiol. 1893;2011(32):2067–72. Covington MF, Chin SS, Osborn AG. Pituicytoma, spindle cell oncocytoma, and granular cell tumor: clarification and meta-analysis of the world literature since. AJNR Am J Neuroradiol. 1893;2011(32):2067–72.
12.
Zurück zum Zitat Rushing EJ, Giangaspero F, Paulus W, Burger PC, Craniopharyngioma LDN, Ohgaki H, Wiestler OD, Cavenee WK. (editors) WHO classification of tumours of the central nervous system. Lyon: IARC Press; 2007, pp 238–40. Rushing EJ, Giangaspero F, Paulus W, Burger PC, Craniopharyngioma LDN, Ohgaki H, Wiestler OD, Cavenee WK. (editors) WHO classification of tumours of the central nervous system. Lyon: IARC Press; 2007, pp 238–40.
13.
Zurück zum Zitat Russell DS, Rubinstein LJ. Pathology of tumours of the nervous system, 5th ed. London: Edward Arnold; 1989, pp 695–704. Russell DS, Rubinstein LJ. Pathology of tumours of the nervous system, 5th ed. London: Edward Arnold; 1989, pp 695–704.
14.
Zurück zum Zitat Hermet M, Delévaux I, Trouillier S, André M, Chazal J, Aumaître O. Pituitary metastasis presenting as diabetes insipidus: a report of four cases and literature review. Rev Med Interne. 2009;30:425–9.CrossRefPubMed Hermet M, Delévaux I, Trouillier S, André M, Chazal J, Aumaître O. Pituitary metastasis presenting as diabetes insipidus: a report of four cases and literature review. Rev Med Interne. 2009;30:425–9.CrossRefPubMed
15.
Zurück zum Zitat Ravnik J, Smigoc T, Bunc G, Lanisnik B, Ksela U, Ravnik M, Velnar T. Hypophyseal metastases: a report of three cases and literature review. Neurol Neurochir Pol. 2016;50:511–6.PubMed Ravnik J, Smigoc T, Bunc G, Lanisnik B, Ksela U, Ravnik M, Velnar T. Hypophyseal metastases: a report of three cases and literature review. Neurol Neurochir Pol. 2016;50:511–6.PubMed
16.
Zurück zum Zitat Taschner CA, Krauss S, Vougiokas V, Weber J, Prinz M. Freiburg neuropathology case conference: a suprasellar mass. Klin Neuroradiol. 2009;19:166–7.CrossRefPubMed Taschner CA, Krauss S, Vougiokas V, Weber J, Prinz M. Freiburg neuropathology case conference: a suprasellar mass. Klin Neuroradiol. 2009;19:166–7.CrossRefPubMed
17.
Zurück zum Zitat Roncaroli F, Scheithauer BW, Cenacchi G, Horvath E, Kovacs K, Lloyd RV, Abell-Aleff P, Santi M, Yates AJ. ‘Spindle cell oncocytoma’ of the adenohypophysis: a tumor of folliculostellate cells? Am J Surg Pathol. 2008;26:1048–55.CrossRef Roncaroli F, Scheithauer BW, Cenacchi G, Horvath E, Kovacs K, Lloyd RV, Abell-Aleff P, Santi M, Yates AJ. ‘Spindle cell oncocytoma’ of the adenohypophysis: a tumor of folliculostellate cells? Am J Surg Pathol. 2008;26:1048–55.CrossRef
18.
Zurück zum Zitat Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW. The 2016 World Health Organization classification of tumors of the central nervous system: a summary. Acta Neuropathol. 2016;131:803–20.CrossRefPubMed Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW. The 2016 World Health Organization classification of tumors of the central nervous system: a summary. Acta Neuropathol. 2016;131:803–20.CrossRefPubMed
19.
Zurück zum Zitat Coiré CI, Horvath E, Smyth HS, Kovacs K. Rapidly recurring folliculostellate cell tumour of the adenohypophysis with the morphology of a spindle cell oncocytoma: case report with electron microscopic studies. Clin Neuropathol. 2009;28:303–8.CrossRefPubMed Coiré CI, Horvath E, Smyth HS, Kovacs K. Rapidly recurring folliculostellate cell tumour of the adenohypophysis with the morphology of a spindle cell oncocytoma: case report with electron microscopic studies. Clin Neuropathol. 2009;28:303–8.CrossRefPubMed
20.
Zurück zum Zitat Kloub O, Perry A, Tu PH, Lipper M, Lopes MB. Spindle cell oncocytoma of the adenohypophysis: report of two recurrent cases. Am J Surg Pathol. 2005;29:247–53.CrossRefPubMed Kloub O, Perry A, Tu PH, Lipper M, Lopes MB. Spindle cell oncocytoma of the adenohypophysis: report of two recurrent cases. Am J Surg Pathol. 2005;29:247–53.CrossRefPubMed
21.
Zurück zum Zitat Vajtai I, Sahli R, Kappeler A. Spindle cell oncocytoma of the adenohypophysis: report of a case with a 16-year follow-up. Pathol Res Pract. 2006;202:745–50.CrossRefPubMed Vajtai I, Sahli R, Kappeler A. Spindle cell oncocytoma of the adenohypophysis: report of a case with a 16-year follow-up. Pathol Res Pract. 2006;202:745–50.CrossRefPubMed
22.
Zurück zum Zitat Mlika M, Azouz H, Chelly I, Saïd IB, Jemel H, Haouet S, Zitouna M, Kchir N. Spindle cell oncocytoma of the adenohypophysis in a woman: a case report and review of the literature. J Med Case Rep. 2006;5:64.CrossRef Mlika M, Azouz H, Chelly I, Saïd IB, Jemel H, Haouet S, Zitouna M, Kchir N. Spindle cell oncocytoma of the adenohypophysis in a woman: a case report and review of the literature. J Med Case Rep. 2006;5:64.CrossRef
23.
Zurück zum Zitat Fujisawa H, Tohma Y, Muramatsu N, Kida S, Kaizaki Y, Tamamura H. Spindle cell oncocytoma of the adenohypophysis with marked hypervascularity. Case report. Neurol Med Chir (Tokyo). 2012;52:594–8.CrossRef Fujisawa H, Tohma Y, Muramatsu N, Kida S, Kaizaki Y, Tamamura H. Spindle cell oncocytoma of the adenohypophysis with marked hypervascularity. Case report. Neurol Med Chir (Tokyo). 2012;52:594–8.CrossRef
24.
Zurück zum Zitat Vuong HG, Kondo T, Tran TM, Oishi N, Nakazawa T, Mochizuki K, Inoue T, Kasai K, Tahara I, Jieying W, Katoh R. Spindle cell oncocytoma of adenohypophysis: report of a case and immunohistochemical review of literature. Pathol Res Pract. 2016;212:222–5.CrossRefPubMed Vuong HG, Kondo T, Tran TM, Oishi N, Nakazawa T, Mochizuki K, Inoue T, Kasai K, Tahara I, Jieying W, Katoh R. Spindle cell oncocytoma of adenohypophysis: report of a case and immunohistochemical review of literature. Pathol Res Pract. 2016;212:222–5.CrossRefPubMed
25.
Zurück zum Zitat Matyja E, Maksymowicz M, Grajkowska W, Olszewski W, Zieliński G, Bonicki W. Spindle cell oncocytoma of the adenohypophysis – a clinicopathological and ultrastructural study of two cases. Folia Neuropathol. 2010;48:175–84.PubMed Matyja E, Maksymowicz M, Grajkowska W, Olszewski W, Zieliński G, Bonicki W. Spindle cell oncocytoma of the adenohypophysis – a clinicopathological and ultrastructural study of two cases. Folia Neuropathol. 2010;48:175–84.PubMed
26.
Zurück zum Zitat Borota OC, Scheithauer BW, Fougner SL, Hald JK, Ramm-Pettersen J, Bollerslev J. Spindle cell oncocytoma of the adenohypophysis: report of a case with marked cellular atypia and recurrence despite adjuvant treatment. Clin Neuropathol. 2009;28:91–5.CrossRefPubMed Borota OC, Scheithauer BW, Fougner SL, Hald JK, Ramm-Pettersen J, Bollerslev J. Spindle cell oncocytoma of the adenohypophysis: report of a case with marked cellular atypia and recurrence despite adjuvant treatment. Clin Neuropathol. 2009;28:91–5.CrossRefPubMed
27.
Zurück zum Zitat Demssie YN, Joseph J, Dawson T, Roberts G, de Carpentier J, Howell S. Recurrent spindle cell oncocytoma of the pituitary, a case report and review of literature. Pituitary. 2011;14:367–70.CrossRefPubMed Demssie YN, Joseph J, Dawson T, Roberts G, de Carpentier J, Howell S. Recurrent spindle cell oncocytoma of the pituitary, a case report and review of literature. Pituitary. 2011;14:367–70.CrossRefPubMed
28.
Zurück zum Zitat Rotman JA, Kucharczyk W, Zadeh G, Kiehl TR, Al-Ahmadi H. Spindle cell oncocytoma of the adenohypophysis: a case report illustrating its natural history with 8‑year observation and a review of the literature. Clin Imaging. 2014;38:499–504.CrossRefPubMed Rotman JA, Kucharczyk W, Zadeh G, Kiehl TR, Al-Ahmadi H. Spindle cell oncocytoma of the adenohypophysis: a case report illustrating its natural history with 8‑year observation and a review of the literature. Clin Imaging. 2014;38:499–504.CrossRefPubMed
Metadaten
Titel
Freiburg Neuropathology Case Conference
A Pituitary Mass Lesion
verfasst von
C. A. Taschner
R. Sankowski
J. M. Shah
H. Urbach
R. Hartmann
M. Prinz
Publikationsdatum
09.11.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Neuroradiology / Ausgabe 4/2016
Print ISSN: 1869-1439
Elektronische ISSN: 1869-1447
DOI
https://doi.org/10.1007/s00062-016-0549-5

Weitere Artikel der Ausgabe 4/2016

Clinical Neuroradiology 4/2016 Zur Ausgabe

Mammakarzinom: Brustdichte beeinflusst rezidivfreies Überleben

26.05.2024 Mammakarzinom Nachrichten

Frauen, die zum Zeitpunkt der Brustkrebsdiagnose eine hohe mammografische Brustdichte aufweisen, haben ein erhöhtes Risiko für ein baldiges Rezidiv, legen neue Daten nahe.

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

Klinikreform soll zehntausende Menschenleben retten

15.05.2024 Klinik aktuell Nachrichten

Gesundheitsminister Lauterbach hat die vom Bundeskabinett beschlossene Klinikreform verteidigt. Kritik an den Plänen kommt vom Marburger Bund. Und in den Ländern wird über den Gang zum Vermittlungsausschuss spekuliert.

Darf man die Behandlung eines Neonazis ablehnen?

08.05.2024 Gesellschaft Nachrichten

In einer Leseranfrage in der Zeitschrift Journal of the American Academy of Dermatology möchte ein anonymer Dermatologe bzw. eine anonyme Dermatologin wissen, ob er oder sie einen Patienten behandeln muss, der eine rassistische Tätowierung trägt.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.