Neurological Functional Independence After Endovascular Thrombectomy and Different Imaging Modalities for Large Infarct Core Assessment

Zurück zum Zitat Kakita H, Yoshimura S, Uchida K, Sakai N, Yamagami H, Morimoto T; RESCUE-Japan Registry 2 Investigators. Impact of Endovascular Therapy in Patients With Large Ischemic Core: Subanalysis of Recovery by Endovascular Salvage for Cerebral Ultra-Acute Embolism Japan Registry 2. Stroke. 2019;50:901–8.PubMed Kakita H, Yoshimura S, Uchida K, Sakai N, Yamagami H, Morimoto T; RESCUE-Japan Registry 2 Investigators. Impact of Endovascular Therapy in Patients With Large Ischemic Core: Subanalysis of Recovery by Endovascular Salvage for Cerebral Ultra-Acute Embolism Japan Registry 2. Stroke. 2019;50:901–8.PubMed

Zurück zum Zitat Kerleroux B, Janot K, Dargazanli C, Daly-Eraya D, Ben-Hassen W, Zhu F, Gory B, Hak JF, Perot C, Detraz L, Bourcier R, Rouchaud A, Forestier G, Benzakoun J, Marnat G, Gariel F, Mordasini P, Kaesmacher J, Boulouis G; JENI Research Collaborative. Perfusion Imaging to Select Patients with Large Ischemic Core for Mechanical Thrombectomy. J Stroke. 2020;22:225–33.PubMedPubMedCentral Kerleroux B, Janot K, Dargazanli C, Daly-Eraya D, Ben-Hassen W, Zhu F, Gory B, Hak JF, Perot C, Detraz L, Bourcier R, Rouchaud A, Forestier G, Benzakoun J, Marnat G, Gariel F, Mordasini P, Kaesmacher J, Boulouis G; JENI Research Collaborative. Perfusion Imaging to Select Patients with Large Ischemic Core for Mechanical Thrombectomy. J Stroke. 2020;22:225–33.PubMedPubMedCentral

Zurück zum Zitat Román LS, Menon BK, Blasco J, Hernández-Pérez M, Dávalos A, Majoie CBLM, Campbell BCV, Guillemin F, Lingsma H, Anxionnat R, Epstein J, Saver JL, Marquering H, Wong JH, Lopes D, Reimann G, Desal H, Dippel DWJ, Coutts S, du Mesnil de Rochemont R, Yavagal D, Ferre JC, Roos YBWEM, Liebeskind DS, Lenthall R, Molina C, Al Ajlan FS, Reddy V, Dowlatshahi D, Sourour NA, Oppenheim C, Mitha AP, Davis SM, Weimar C, van Oostenbrugge RJ, Cobo E, Kleinig TJ, Donnan GA, van der Lugt A, Demchuk AM, Berkhemer OA, Boers AMM, Ford GA, Muir KW, Brown BS, Jovin T, van Zwam WH, Mitchell PJ, Hill MD, White P, Bracard S, Goyal M; HERMES collaborators. Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data. Lancet Neurol. 2018;17:895–904. Erratum in: Lancet Neurol. 2018;17:e2–3.PubMed Román LS, Menon BK, Blasco J, Hernández-Pérez M, Dávalos A, Majoie CBLM, Campbell BCV, Guillemin F, Lingsma H, Anxionnat R, Epstein J, Saver JL, Marquering H, Wong JH, Lopes D, Reimann G, Desal H, Dippel DWJ, Coutts S, du Mesnil de Rochemont R, Yavagal D, Ferre JC, Roos YBWEM, Liebeskind DS, Lenthall R, Molina C, Al Ajlan FS, Reddy V, Dowlatshahi D, Sourour NA, Oppenheim C, Mitha AP, Davis SM, Weimar C, van Oostenbrugge RJ, Cobo E, Kleinig TJ, Donnan GA, van der Lugt A, Demchuk AM, Berkhemer OA, Boers AMM, Ford GA, Muir KW, Brown BS, Jovin T, van Zwam WH, Mitchell PJ, Hill MD, White P, Bracard S, Goyal M; HERMES collaborators. Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data. Lancet Neurol. 2018;17:895–904. Erratum in: Lancet Neurol. 2018;17:e2–3.PubMed

Zurück zum Zitat Bhuva P, Yoo AJ, Jadhav AP, Jovin TG, Haussen DC, Bonafe A, Budzik RJ, Yavagal DR, Hanel RA, Hassan AE, Ribo M, Cognard C, Sila CA, Morgan PM, Zhang Y, Shields R, Smith W, Saver JL, Liebeskind DS, Nogueira RG; DAWN Trial Investigators. Noncontrast Computed Tomography Alberta Stroke Program Early CT Score May Modify Intra-Arterial Treatment Effect in DAWN. Stroke. 2019;50:2404–12.PubMed Bhuva P, Yoo AJ, Jadhav AP, Jovin TG, Haussen DC, Bonafe A, Budzik RJ, Yavagal DR, Hanel RA, Hassan AE, Ribo M, Cognard C, Sila CA, Morgan PM, Zhang Y, Shields R, Smith W, Saver JL, Liebeskind DS, Nogueira RG; DAWN Trial Investigators. Noncontrast Computed Tomography Alberta Stroke Program Early CT Score May Modify Intra-Arterial Treatment Effect in DAWN. Stroke. 2019;50:2404–12.PubMed

Zurück zum Zitat Bouslama M, Barreira CM, Haussen DC, Rodrigues GM, Pisani L, Frankel MR, Nogueira RG. Endovascular reperfusion outcomes in patients with a stroke and low ASPECTS is highly dependent on baseline infarct volumes. J Neurointerv Surg. 2022;14:117–21.PubMed Bouslama M, Barreira CM, Haussen DC, Rodrigues GM, Pisani L, Frankel MR, Nogueira RG. Endovascular reperfusion outcomes in patients with a stroke and low ASPECTS is highly dependent on baseline infarct volumes. J Neurointerv Surg. 2022;14:117–21.PubMed

Zurück zum Zitat Campbell BCV, Majoie CBLM, Albers GW, Menon BK, Yassi N, Sharma G, van Zwam WH, van Oostenbrugge RJ, Demchuk AM, Guillemin F, White P, Dávalos A, van der Lugt A, Butcher KS, Cherifi A, Marquering HA, Cloud G, Macho Fernández JM, Madigan J, Oppenheim C, Donnan GA, Roos YBWEM, Shankar J, Lingsma H, Bonafé A, Raoult H, Hernández-Pérez M, Bharatha A, Jahan R, Jansen O, Richard S, Levy EI, Berkhemer OA, Soudant M, Aja L, Davis SM, Krings T, Tisserand M, San Román L, Tomasello A, Beumer D, Brown S, Liebeskind DS, Bracard S, Muir KW, Dippel DWJ, Goyal M, Saver JL, Jovin TG, Hill MD, Mitchell PJ; HERMES collaborators. Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a meta-analysis of individual patient-level data. Lancet Neurol. 2019;18:46–55. Erratum in: Lancet Neurol. 2019;18:e2.PubMed Campbell BCV, Majoie CBLM, Albers GW, Menon BK, Yassi N, Sharma G, van Zwam WH, van Oostenbrugge RJ, Demchuk AM, Guillemin F, White P, Dávalos A, van der Lugt A, Butcher KS, Cherifi A, Marquering HA, Cloud G, Macho Fernández JM, Madigan J, Oppenheim C, Donnan GA, Roos YBWEM, Shankar J, Lingsma H, Bonafé A, Raoult H, Hernández-Pérez M, Bharatha A, Jahan R, Jansen O, Richard S, Levy EI, Berkhemer OA, Soudant M, Aja L, Davis SM, Krings T, Tisserand M, San Román L, Tomasello A, Beumer D, Brown S, Liebeskind DS, Bracard S, Muir KW, Dippel DWJ, Goyal M, Saver JL, Jovin TG, Hill MD, Mitchell PJ; HERMES collaborators. Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a meta-analysis of individual patient-level data. Lancet Neurol. 2019;18:46–55. Erratum in: Lancet Neurol. 2019;18:e2.PubMed

Zurück zum Zitat Haussen DC, Dehkharghani S, Rangaraju S, Rebello LC, Bouslama M, Grossberg JA, Anderson A, Belagaje S, Frankel M, Nogueira RG. Automated CT Perfusion Ischemic Core Volume and Noncontrast CT ASPECTS (Alberta Stroke Program Early CT Score): Correlation and Clinical Outcome Prediction in Large Vessel Stroke. Stroke. 2016;47:2318–22.PubMed Haussen DC, Dehkharghani S, Rangaraju S, Rebello LC, Bouslama M, Grossberg JA, Anderson A, Belagaje S, Frankel M, Nogueira RG. Automated CT Perfusion Ischemic Core Volume and Noncontrast CT ASPECTS (Alberta Stroke Program Early CT Score): Correlation and Clinical Outcome Prediction in Large Vessel Stroke. Stroke. 2016;47:2318–22.PubMed

Zurück zum Zitat Kaesmacher J, Chaloulos-Iakovidis P, Panos L, Mordasini P, Michel P, Hajdu SD, Ribo M, Requena M, Maegerlein C, Friedrich B, Costalat V, Benali A, Pierot L, Gawlitza M, Schaafsma J, Mendes Pereira V, Gralla J, Fischer U. Mechanical Thrombectomy in Ischemic Stroke Patients With Alberta Stroke Program Early Computed Tomography Score 0-5. Stroke. 2019;50:880–8.PubMedPubMedCentral Kaesmacher J, Chaloulos-Iakovidis P, Panos L, Mordasini P, Michel P, Hajdu SD, Ribo M, Requena M, Maegerlein C, Friedrich B, Costalat V, Benali A, Pierot L, Gawlitza M, Schaafsma J, Mendes Pereira V, Gralla J, Fischer U. Mechanical Thrombectomy in Ischemic Stroke Patients With Alberta Stroke Program Early Computed Tomography Score 0-5. Stroke. 2019;50:880–8.PubMedPubMedCentral

Zurück zum Zitat Sarraj A, Hassan AE, Savitz S, Sitton C, Grotta J, Chen P, Cai C, Cutter G, Imam B, Reddy S, Parsha K, Pujara D, Riascos R, Vora N, Abraham M, Kamal H, Haussen DC, Barreto AD, Lansberg M, Gupta R, Albers GW. Outcomes of Endovascular Thrombectomy vs Medical Management Alone in Patients With Large Ischemic Cores: A Secondary Analysis of the Optimizing Patient’s Selection for Endovascular Treatment in Acute Ischemic Stroke (SELECT) Study. JAMA Neurol. 2019;76:1147–56.PubMedPubMedCentral Sarraj A, Hassan AE, Savitz S, Sitton C, Grotta J, Chen P, Cai C, Cutter G, Imam B, Reddy S, Parsha K, Pujara D, Riascos R, Vora N, Abraham M, Kamal H, Haussen DC, Barreto AD, Lansberg M, Gupta R, Albers GW. Outcomes of Endovascular Thrombectomy vs Medical Management Alone in Patients With Large Ischemic Cores: A Secondary Analysis of the Optimizing Patient’s Selection for Endovascular Treatment in Acute Ischemic Stroke (SELECT) Study. JAMA Neurol. 2019;76:1147–56.PubMedPubMedCentral

Zurück zum Zitat Desilles JP, Consoli A, Redjem H, Coskun O, Ciccio G, Smajda S, Labreuche J, Preda C, Ruiz Guerrero C, Decroix JP, Rodesch G, Mazighi M, Blanc R, Piotin M, Lapergue B; ETIS (Endovascular Treatment in Ischemic Stroke) Research Investigators. Successful Reperfusion With Mechanical Thrombectomy Is Associated With Reduced Disability and Mortality in Patients With Pretreatment Diffusion-Weighted Imaging-Alberta Stroke Program Early Computed Tomography Score ≤6. Stroke. 2017;48:963–9. Erratum in: Stroke. 2017;48:e120. Erratum in: Stroke. 2017;48:e138.PubMed Desilles JP, Consoli A, Redjem H, Coskun O, Ciccio G, Smajda S, Labreuche J, Preda C, Ruiz Guerrero C, Decroix JP, Rodesch G, Mazighi M, Blanc R, Piotin M, Lapergue B; ETIS (Endovascular Treatment in Ischemic Stroke) Research Investigators. Successful Reperfusion With Mechanical Thrombectomy Is Associated With Reduced Disability and Mortality in Patients With Pretreatment Diffusion-Weighted Imaging-Alberta Stroke Program Early Computed Tomography Score ≤6. Stroke. 2017;48:963–9. Erratum in: Stroke. 2017;48:e120. Erratum in: Stroke. 2017;48:e138.PubMed

Zurück zum Zitat Rebello LC, Bouslama M, Haussen DC, Dehkharghani S, Grossberg JA, Belagaje S, Frankel MR, Nogueira RG. Endovascular Treatment for Patients With Acute Stroke Who Have a Large Ischemic Core and Large Mismatch Imaging Profile. JAMA Neurol. 2017;74:34–40.PubMed Rebello LC, Bouslama M, Haussen DC, Dehkharghani S, Grossberg JA, Belagaje S, Frankel MR, Nogueira RG. Endovascular Treatment for Patients With Acute Stroke Who Have a Large Ischemic Core and Large Mismatch Imaging Profile. JAMA Neurol. 2017;74:34–40.PubMed

Zurück zum Zitat Chen Z, Zhang R, Zhou Y, Gong X, Zhang M, Shi F, Yu X, Lou M. Patients With Ischemic Core ≥70 ml Within 6 h of Symptom Onset May Still Benefit From Endovascular Treatment. Front Neurol. 2018;9:933.PubMedPubMedCentral Chen Z, Zhang R, Zhou Y, Gong X, Zhang M, Shi F, Yu X, Lou M. Patients With Ischemic Core ≥70 ml Within 6 h of Symptom Onset May Still Benefit From Endovascular Treatment. Front Neurol. 2018;9:933.PubMedPubMedCentral

Zurück zum Zitat Seners P, Oppenheim C, Turc G, Albucher JF, Guenego A, Raposo N, Christensen S, Calvière L, Viguier A, Darcourt J, Januel AC, Mlynash M, Sommet A, Thalamas C, Sibon I, Rousseau V, Tourdias T, Menegon P, Bonneville F, Mazighi M, Charron S, Legrand L, Cognard C, Albers GW, Baron JC, Olivot JM; FRAME investigators. Perfusion Imaging and Clinical Outcome in Acute Ischemic Stroke with Large Core. Ann Neurol. 2021;90:417–27.PubMed Seners P, Oppenheim C, Turc G, Albucher JF, Guenego A, Raposo N, Christensen S, Calvière L, Viguier A, Darcourt J, Januel AC, Mlynash M, Sommet A, Thalamas C, Sibon I, Rousseau V, Tourdias T, Menegon P, Bonneville F, Mazighi M, Charron S, Legrand L, Cognard C, Albers GW, Baron JC, Olivot JM; FRAME investigators. Perfusion Imaging and Clinical Outcome in Acute Ischemic Stroke with Large Core. Ann Neurol. 2021;90:417–27.PubMed

Zurück zum Zitat Gilgen MD, Klimek D, Liesirova KT, Meisterernst J, Klinger-Gratz PP, Schroth G, Mordasini P, Hsieh K, Slotboom J, Heldner MR, Broeg-Morvay A, Mono ML, Fischer U, Mattle HP, Arnold M, Gralla J, El-Koussy M, Jung S. Younger Stroke Patients With Large Pretreatment Diffusion-Weighted Imaging Lesions May Benefit From Endovascular Treatment. Stroke. 2015;46:2510–6.PubMed Gilgen MD, Klimek D, Liesirova KT, Meisterernst J, Klinger-Gratz PP, Schroth G, Mordasini P, Hsieh K, Slotboom J, Heldner MR, Broeg-Morvay A, Mono ML, Fischer U, Mattle HP, Arnold M, Gralla J, El-Koussy M, Jung S. Younger Stroke Patients With Large Pretreatment Diffusion-Weighted Imaging Lesions May Benefit From Endovascular Treatment. Stroke. 2015;46:2510–6.PubMed

Zurück zum Zitat Gautheron V, Xie Y, Tisserand M, Raoult H, Soize S, Naggara O, Bourcier R, Richard S, Guillemin F, Bracard S, Oppenheim C. Outcome After Reperfusion Therapies in Patients With Large Baseline Diffusion-Weighted Imaging Stroke Lesions: A THRACE Trial (Mechanical Thrombectomy After Intravenous Alteplase Versus Alteplase Alone After Stroke) Subgroup Analysis. Stroke. 2018;49:750–3.PubMed Gautheron V, Xie Y, Tisserand M, Raoult H, Soize S, Naggara O, Bourcier R, Richard S, Guillemin F, Bracard S, Oppenheim C. Outcome After Reperfusion Therapies in Patients With Large Baseline Diffusion-Weighted Imaging Stroke Lesions: A THRACE Trial (Mechanical Thrombectomy After Intravenous Alteplase Versus Alteplase Alone After Stroke) Subgroup Analysis. Stroke. 2018;49:750–3.PubMed

Zurück zum Zitat Panni P, Michelozzi C, Blanc R, Chen B, Consoli A, Mazighi M, Piotin M, Dargazanli C, Arquizan C, Marnat G, Sibon I, Anxionnat R, Richard S, Hossu G, Bourcier R, Lapergue B, Gory B; ETIS (Endovascular Treatment in Ischemic Stroke) Investigators. The role of infarct location in patients with DWI-ASPECTS 0-5 acute stroke treated with thrombectomy. Neurology. 2020;95:e3344–54.PubMed Panni P, Michelozzi C, Blanc R, Chen B, Consoli A, Mazighi M, Piotin M, Dargazanli C, Arquizan C, Marnat G, Sibon I, Anxionnat R, Richard S, Hossu G, Bourcier R, Lapergue B, Gory B; ETIS (Endovascular Treatment in Ischemic Stroke) Investigators. The role of infarct location in patients with DWI-ASPECTS 0-5 acute stroke treated with thrombectomy. Neurology. 2020;95:e3344–54.PubMed

Zurück zum Zitat Sabben C, Desilles JP, Charbonneau F, Savatovsky J, Morvan E, Obadia A, Raynouard I, Fela F, Escalard S, Redjem H, Smajda S, Ciccio G, Blanc R, Fahed R, Le Guerinel C, Engrand N, Ben Maacha M, Labreuche J, Mazighi M, Piotin M, Obadia M. Early successful reperfusion after endovascular therapy reduces malignant middle cerebral artery infarction occurrence in young patients with large diffusion-weighted imaging lesions. Eur J Neurol. 2020;27:1988–95.PubMed Sabben C, Desilles JP, Charbonneau F, Savatovsky J, Morvan E, Obadia A, Raynouard I, Fela F, Escalard S, Redjem H, Smajda S, Ciccio G, Blanc R, Fahed R, Le Guerinel C, Engrand N, Ben Maacha M, Labreuche J, Mazighi M, Piotin M, Obadia M. Early successful reperfusion after endovascular therapy reduces malignant middle cerebral artery infarction occurrence in young patients with large diffusion-weighted imaging lesions. Eur J Neurol. 2020;27:1988–95.PubMed

Zurück zum Zitat Broocks G, Hanning U, Flottmann F, Schönfeld M, Faizy TD, Sporns P, Baumgart M, Leischner H, Schön G, Minnerup J, Thomalla G, Fiehler J, Kemmling A. Clinical benefit of thrombectomy in stroke patients with low ASPECTS is mediated by oedema reduction. Brain. 2019;142:1399–1407. Erratum in: Brain. 2019;142:e26.PubMed Broocks G, Hanning U, Flottmann F, Schönfeld M, Faizy TD, Sporns P, Baumgart M, Leischner H, Schön G, Minnerup J, Thomalla G, Fiehler J, Kemmling A. Clinical benefit of thrombectomy in stroke patients with low ASPECTS is mediated by oedema reduction. Brain. 2019;142:1399–1407. Erratum in: Brain. 2019;142:e26.PubMed

Zurück zum Zitat Deb-Chatterji M, Pinnschmidt H, Flottmann F, Leischner H, Broocks G, Alegiani A, Brekenfeld C, Fiehler J, Gerloff C, Thomalla G; GSR-ET Investigators. Predictors of independent outcome of thrombectomy in stroke patients with large baseline infarcts in clinical practice: a multicenter analysis. J Neurointerv Surg. 2020;12:1064–8.PubMed Deb-Chatterji M, Pinnschmidt H, Flottmann F, Leischner H, Broocks G, Alegiani A, Brekenfeld C, Fiehler J, Gerloff C, Thomalla G; GSR-ET Investigators. Predictors of independent outcome of thrombectomy in stroke patients with large baseline infarcts in clinical practice: a multicenter analysis. J Neurointerv Surg. 2020;12:1064–8.PubMed

Zurück zum Zitat Jiang S, Peng Y, Jing CH, Fei AH, Wang HR, Gao CJ, Chen M, Li Y, Pan S. Endovascular thrombectomy can be beneficial to acute ischemic stroke patients with large infarcts. J Neurosurg. 2018;130:1383–90. Jiang S, Peng Y, Jing CH, Fei AH, Wang HR, Gao CJ, Chen M, Li Y, Pan S. Endovascular thrombectomy can be beneficial to acute ischemic stroke patients with large infarcts. J Neurosurg. 2018;130:1383–90.

Zurück zum Zitat Kim JT, Goyal M, Levy EI, Liebeskind D, Jahan R, Pereira VM, Gralla J, Bonafe A, Saver JL. Onset to reperfusion time as a determinant of outcomes across a wide range of ASPECTS in endovascular thrombectomy: pooled analysis of the SWIFT, SWIFT PRIME, and STAR studies. J Neurointerv Surg. 2020;12:240–5.PubMed Kim JT, Goyal M, Levy EI, Liebeskind D, Jahan R, Pereira VM, Gralla J, Bonafe A, Saver JL. Onset to reperfusion time as a determinant of outcomes across a wide range of ASPECTS in endovascular thrombectomy: pooled analysis of the SWIFT, SWIFT PRIME, and STAR studies. J Neurointerv Surg. 2020;12:240–5.PubMed

Zurück zum Zitat Lei C, Zhou X, Chang X, Zhao Q, Zhong L. Mechanical Thrombectomy in Patients with Acute Ischemic Stroke and ASPECTS ≤5. J Stroke Cerebrovasc Dis. 2021;30:105748.PubMed Lei C, Zhou X, Chang X, Zhao Q, Zhong L. Mechanical Thrombectomy in Patients with Acute Ischemic Stroke and ASPECTS ≤5. J Stroke Cerebrovasc Dis. 2021;30:105748.PubMed

Zurück zum Zitat Ospel J, Kappelhof M, Groot AE, LeCouffe NE, Coutinho JM, Yoo AJ, Yo LSF, Beenen LFM, van Zwam WH, van der Lugt A, Postma AA, Roos YBWEM, Goyal M, Majoie CBLM; MR CLEAN Registry Investigators†. Combined Effect of Age and Baseline Alberta Stroke Program Early Computed Tomography Score on Post-Thrombectomy Clinical Outcomes in the MR CLEAN Registry. Stroke. 2020;51:3742–5.PubMed Ospel J, Kappelhof M, Groot AE, LeCouffe NE, Coutinho JM, Yoo AJ, Yo LSF, Beenen LFM, van Zwam WH, van der Lugt A, Postma AA, Roos YBWEM, Goyal M, Majoie CBLM; MR CLEAN Registry Investigators†. Combined Effect of Age and Baseline Alberta Stroke Program Early Computed Tomography Score on Post-Thrombectomy Clinical Outcomes in the MR CLEAN Registry. Stroke. 2020;51:3742–5.PubMed

Zurück zum Zitat Siegler JE, Messé SR, Sucharew H, Kasner SE, Mehta T, Arora N, Starosciak AK, De Los Rios La Rosa F, Barnhill NR, Mistry AM, Patel K, Assad S, Tarboosh A, Dakay K, Salwi S, Wagner J, Bennett A, Jagadeesan BD, Streib C, Weber SA, Chitale R, Volpi JJ, Mayer SA, Yaghi S, Jayaraman M, Khatri P, Mistry EA. Thrombectomy in DAWN- and DEFUSE-3-Ineligible Patients: A Subgroup Analysis From the BEST Prospective Cohort Study. Neurosurgery. 2020;86:E156–63.PubMed Siegler JE, Messé SR, Sucharew H, Kasner SE, Mehta T, Arora N, Starosciak AK, De Los Rios La Rosa F, Barnhill NR, Mistry AM, Patel K, Assad S, Tarboosh A, Dakay K, Salwi S, Wagner J, Bennett A, Jagadeesan BD, Streib C, Weber SA, Chitale R, Volpi JJ, Mayer SA, Yaghi S, Jayaraman M, Khatri P, Mistry EA. Thrombectomy in DAWN- and DEFUSE-3-Ineligible Patients: A Subgroup Analysis From the BEST Prospective Cohort Study. Neurosurgery. 2020;86:E156–63.PubMed

Zurück zum Zitat Zaidat OO, Liebeskind DS, Jadhav AP, Ortega-Gutierrez S, Nguyen TN, Haussen DC, Yavagal DR, Froehler MT, Jahan R, Nogueira RG, Yao TL, Alenzi BA, Bushnaq S, Mueller-Kronast NH. Impact of Age and Alberta Stroke Program Early Computed Tomography Score 0 to 5 on Mechanical Thrombectomy Outcomes: Analysis From the STRATIS Registry. Stroke. 2021;52:2220–8.PubMedPubMedCentral Zaidat OO, Liebeskind DS, Jadhav AP, Ortega-Gutierrez S, Nguyen TN, Haussen DC, Yavagal DR, Froehler MT, Jahan R, Nogueira RG, Yao TL, Alenzi BA, Bushnaq S, Mueller-Kronast NH. Impact of Age and Alberta Stroke Program Early Computed Tomography Score 0 to 5 on Mechanical Thrombectomy Outcomes: Analysis From the STRATIS Registry. Stroke. 2021;52:2220–8.PubMedPubMedCentral

Zurück zum Zitat Hungerford JP, Hyer M, Turk AS, Turner RD, Chaudry MI, Fargen KM, Spiotta AM. Impact of ASPECT scores and infarct distribution on outcomes among patients undergoing thrombectomy for acute ischemic stroke with the ADAPT technique. J Neurointerv Surg. 2017;9:823–9.PubMed Hungerford JP, Hyer M, Turk AS, Turner RD, Chaudry MI, Fargen KM, Spiotta AM. Impact of ASPECT scores and infarct distribution on outcomes among patients undergoing thrombectomy for acute ischemic stroke with the ADAPT technique. J Neurointerv Surg. 2017;9:823–9.PubMed

Zurück zum Zitat Logan C, Maingard J, Phan K, Motyer R, Barras C, Looby S, Brennan P, O’Hare A, Brooks DM, Chandra RV, Asadi H, Kok HK, Thornton J. Borderline Alberta Stroke Programme Early CT Score Patients with Acute Ischemic Stroke Due to Large Vessel Occlusion May Find Benefit with Endovascular Thrombectomy. World Neurosurg. 2018;110:e653–8.PubMed Logan C, Maingard J, Phan K, Motyer R, Barras C, Looby S, Brennan P, O’Hare A, Brooks DM, Chandra RV, Asadi H, Kok HK, Thornton J. Borderline Alberta Stroke Programme Early CT Score Patients with Acute Ischemic Stroke Due to Large Vessel Occlusion May Find Benefit with Endovascular Thrombectomy. World Neurosurg. 2018;110:e653–8.PubMed

Zurück zum Zitat Spiotta AM, Vargas J, Hawk H, Turner R, Chaudry MI, Battenhouse H, Turk AS. Impact of the ASPECT scores and distribution on outcome among patients undergoing thrombectomy for acute ischemic stroke. J Neurointerv Surg. 2015;7:551–8.PubMed Spiotta AM, Vargas J, Hawk H, Turner R, Chaudry MI, Battenhouse H, Turk AS. Impact of the ASPECT scores and distribution on outcome among patients undergoing thrombectomy for acute ischemic stroke. J Neurointerv Surg. 2015;7:551–8.PubMed

Zurück zum Zitat Deguchi I, Dembo T, Yoshimura S, Sakai N, Okada Y, Kitagawa K, Kimura K, Hyogo T, Yamagami H, Egashira Y, Tanahashi N. Relationship between magnetic resonance angiography-diffusion-weighted imaging mismatch and clinical outcome in endovascular treatment for acute ischemic stroke: subgroup analysis of the Recovery by Endovascular Salvage for Cerebral Ultra-acute Embolism—Japan Registry. J Stroke Cerebrovasc Dis. 2014;23:1471–6.PubMed Deguchi I, Dembo T, Yoshimura S, Sakai N, Okada Y, Kitagawa K, Kimura K, Hyogo T, Yamagami H, Egashira Y, Tanahashi N. Relationship between magnetic resonance angiography-diffusion-weighted imaging mismatch and clinical outcome in endovascular treatment for acute ischemic stroke: subgroup analysis of the Recovery by Endovascular Salvage for Cerebral Ultra-acute Embolism—Japan Registry. J Stroke Cerebrovasc Dis. 2014;23:1471–6.PubMed

Zurück zum Zitat Inoue M, Olivot JM, Labreuche J, Mlynash M, Tai W, Albucher JF, Meseguer E, Amarenco P, Mazighi M. Impact of diffusion-weighted imaging Alberta stroke program early computed tomography score on the success of endovascular reperfusion therapy. Stroke. 2014;45:1992–8.PubMed Inoue M, Olivot JM, Labreuche J, Mlynash M, Tai W, Albucher JF, Meseguer E, Amarenco P, Mazighi M. Impact of diffusion-weighted imaging Alberta stroke program early computed tomography score on the success of endovascular reperfusion therapy. Stroke. 2014;45:1992–8.PubMed

Zurück zum Zitat Manceau PF, Soize S, Gawlitza M, Fabre G, Bakchine S, Durot C, Serre I, Metaxas GE, Pierot L. Is there a benefit of mechanical thrombectomy in patients with large stroke (DWI-ASPECTS ≤ 5)? Eur J Neurol. 2018;25:105–10.PubMed Manceau PF, Soize S, Gawlitza M, Fabre G, Bakchine S, Durot C, Serre I, Metaxas GE, Pierot L. Is there a benefit of mechanical thrombectomy in patients with large stroke (DWI-ASPECTS ≤ 5)? Eur J Neurol. 2018;25:105–10.PubMed

Zurück zum Zitat Mourand I, Abergel E, Mantilla D, Ayrignac X, Sacagiu T, Eker OF, Gascou G, Dargazanli C, Riquelme C, Moynier M, Bonafé A, Arquizan C, Costalat V. Favorable revascularization therapy in patients with ASPECTS ≤ 5 on DWI in anterior circulation stroke. J Neurointerv Surg. 2018;10:5–9.PubMed Mourand I, Abergel E, Mantilla D, Ayrignac X, Sacagiu T, Eker OF, Gascou G, Dargazanli C, Riquelme C, Moynier M, Bonafé A, Arquizan C, Costalat V. Favorable revascularization therapy in patients with ASPECTS ≤ 5 on DWI in anterior circulation stroke. J Neurointerv Surg. 2018;10:5–9.PubMed

Zurück zum Zitat Song K, Guan M, Li W, Jing Z, Xie X, Shi C, Liang J, Qiao H, Huang L. Acute ischemic stroke patients with diffusion-weighted imaging-Alberta Stroke Program Early Computed Tomography Score ≤ 5 can benefit from endovascular treatment: a single-center experience and literature review. Neuroradiology. 2019;61:451–9.PubMedPubMedCentral Song K, Guan M, Li W, Jing Z, Xie X, Shi C, Liang J, Qiao H, Huang L. Acute ischemic stroke patients with diffusion-weighted imaging-Alberta Stroke Program Early Computed Tomography Score ≤ 5 can benefit from endovascular treatment: a single-center experience and literature review. Neuroradiology. 2019;61:451–9.PubMedPubMedCentral

Zurück zum Zitat Ohta T, Morimoto M, Okada K, Fukuda M, Onishi H, Masahira N, Matsuoka T, Tsuno T, Takemura M. Mechanical Thrombectomy in Anterior Circulation Occlusion Could Be More Effective than Medical Management Even in Low DWI-ASPECTS Patients. Neurol Med Chir (Tokyo). 2018;58:156–63.PubMed Ohta T, Morimoto M, Okada K, Fukuda M, Onishi H, Masahira N, Matsuoka T, Tsuno T, Takemura M. Mechanical Thrombectomy in Anterior Circulation Occlusion Could Be More Effective than Medical Management Even in Low DWI-ASPECTS Patients. Neurol Med Chir (Tokyo). 2018;58:156–63.PubMed

Zurück zum Zitat Shamseer L, Moher D, Clarke M, Ghersi D, Liberati A, Petticrew M, Shekelle P, Stewart LA; PRISMA-P Group. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ. 2015;350:g7647. Shamseer L, Moher D, Clarke M, Ghersi D, Liberati A, Petticrew M, Shekelle P, Stewart LA; PRISMA-P Group. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ. 2015;350:g7647.

Zurück zum Zitat Sarraj A, Grotta JC, Pujara DK, Shaker F, Tsivgoulis G. Triage imaging and outcome measures for large core stroke thrombectomy – a systematic review and meta-analysis. J Neurointerv Surg. 2020;12:1172–9.PubMed Sarraj A, Grotta JC, Pujara DK, Shaker F, Tsivgoulis G. Triage imaging and outcome measures for large core stroke thrombectomy – a systematic review and meta-analysis. J Neurointerv Surg. 2020;12:1172–9.PubMed

Zurück zum Zitat Geuskens RR, Borst J, Lucas M, Boers AM, Berkhemer OA, Roos YB, van Walderveen MA, Jenniskens SF, van Zwam WH, Dippel DW, Majoie CB, Marquering HA; MR CLEAN trial investigators(www.mrclean-trial.org). Characteristics of Misclassified CT Perfusion Ischemic Core in Patients with Acute Ischemic Stroke. PLoS One. 2015;10:e0141571.PubMedPubMedCentral Geuskens RR, Borst J, Lucas M, Boers AM, Berkhemer OA, Roos YB, van Walderveen MA, Jenniskens SF, van Zwam WH, Dippel DW, Majoie CB, Marquering HA; MR CLEAN trial investigators(www.mrclean-trial.org). Characteristics of Misclassified CT Perfusion Ischemic Core in Patients with Acute Ischemic Stroke. PLoS One. 2015;10:e0141571.PubMedPubMedCentral

Zurück zum Zitat Boned S, Padroni M, Rubiera M, Tomasello A, Coscojuela P, Romero N, Muchada M, Rodríguez-Luna D, Flores A, Rodríguez N, Juega J, Pagola J, Alvarez-Sabin J, Molina CA, Ribó M. Admission CT perfusion may overestimate initial infarct core: the ghost infarct core concept. J Neurointerv Surg. 2017;9:66–9.PubMed Boned S, Padroni M, Rubiera M, Tomasello A, Coscojuela P, Romero N, Muchada M, Rodríguez-Luna D, Flores A, Rodríguez N, Juega J, Pagola J, Alvarez-Sabin J, Molina CA, Ribó M. Admission CT perfusion may overestimate initial infarct core: the ghost infarct core concept. J Neurointerv Surg. 2017;9:66–9.PubMed

Zurück zum Zitat Bivard A, Kleinig T, Miteff F, Butcher K, Lin L, Levi C, Parsons M. Ischemic core thresholds change with time to reperfusion: A case control study. Ann Neurol. 2017;82:995–1003.PubMedPubMedCentral Bivard A, Kleinig T, Miteff F, Butcher K, Lin L, Levi C, Parsons M. Ischemic core thresholds change with time to reperfusion: A case control study. Ann Neurol. 2017;82:995–1003.PubMedPubMedCentral

Zurück zum Zitat Qiu W, Kuang H, Lee TY, Boers AM, Brown S, Muir K, Majoie CBLM, Dippel DWJ, White P, Guillemin F, Mitchell PJ, Dávalos A, Bracard S, Campbell B, Saver JL, Jovin TG, Hill MD, Demchuk AM, Goyal M, Menon BK. Confirmatory Study of Time-Dependent Computed Tomographic Perfusion Thresholds for Use in Acute Ischemic Stroke. Stroke. 2019;50:3269–73.PubMed Qiu W, Kuang H, Lee TY, Boers AM, Brown S, Muir K, Majoie CBLM, Dippel DWJ, White P, Guillemin F, Mitchell PJ, Dávalos A, Bracard S, Campbell B, Saver JL, Jovin TG, Hill MD, Demchuk AM, Goyal M, Menon BK. Confirmatory Study of Time-Dependent Computed Tomographic Perfusion Thresholds for Use in Acute Ischemic Stroke. Stroke. 2019;50:3269–73.PubMed

Zurück zum Zitat Laredo C, Renú A, Tudela R, Lopez-Rueda A, Urra X, Llull L, Macías NG, Rudilosso S, Obach V, Amaro S, Chamorro Á. The accuracy of ischemic core perfusion thresholds varies according to time to recanalization in stroke patients treated with mechanical thrombectomy: A comprehensive whole-brain computed tomography perfusion study. J Cereb Blood Flow Metab. 2020;40:966–77.PubMed Laredo C, Renú A, Tudela R, Lopez-Rueda A, Urra X, Llull L, Macías NG, Rudilosso S, Obach V, Amaro S, Chamorro Á. The accuracy of ischemic core perfusion thresholds varies according to time to recanalization in stroke patients treated with mechanical thrombectomy: A comprehensive whole-brain computed tomography perfusion study. J Cereb Blood Flow Metab. 2020;40:966–77.PubMed

Zurück zum Zitat Austein F, Riedel C, Kerby T, Meyne J, Binder A, Lindner T, Huhndorf M, Wodarg F, Jansen O. Comparison of Perfusion CT Software to Predict the Final Infarct Volume After Thrombectomy. Stroke. 2016;47:2311–7.PubMed Austein F, Riedel C, Kerby T, Meyne J, Binder A, Lindner T, Huhndorf M, Wodarg F, Jansen O. Comparison of Perfusion CT Software to Predict the Final Infarct Volume After Thrombectomy. Stroke. 2016;47:2311–7.PubMed

Zurück zum Zitat Phan TG, Donnan GA, Koga M, Mitchell LA, Molan M, Fitt G, Chong W, Holt M, Reutens DC. The ASPECTS template is weighted in favor of the striatocapsular region. Neuroimage. 2006;31:477–81.PubMed Phan TG, Donnan GA, Koga M, Mitchell LA, Molan M, Fitt G, Chong W, Holt M, Reutens DC. The ASPECTS template is weighted in favor of the striatocapsular region. Neuroimage. 2006;31:477–81.PubMed

Zurück zum Zitat Yoshimoto T, Inoue M, Yamagami H, Fujita K, Tanaka K, Ando D, Sonoda K, Kamogawa N, Koga M, Ihara M, Toyoda K. Use of Diffusion-Weighted Imaging-Alberta Stroke Program Early Computed Tomography Score (DWI-ASPECTS) and Ischemic Core Volume to Determine the Malignant Profile in Acute Stroke. J Am Heart Assoc. 2019;8:e012558.PubMedPubMedCentral Yoshimoto T, Inoue M, Yamagami H, Fujita K, Tanaka K, Ando D, Sonoda K, Kamogawa N, Koga M, Ihara M, Toyoda K. Use of Diffusion-Weighted Imaging-Alberta Stroke Program Early Computed Tomography Score (DWI-ASPECTS) and Ischemic Core Volume to Determine the Malignant Profile in Acute Stroke. J Am Heart Assoc. 2019;8:e012558.PubMedPubMedCentral

Zurück zum Zitat Nezu T, Koga M, Nakagawara J, Shiokawa Y, Yamagami H, Furui E, Kimura K, Hasegawa Y, Okada Y, Okuda S, Kario K, Naganuma M, Maeda K, Minematsu K, Toyoda K. Early ischemic change on CT versus diffusion-weighted imaging for patients with stroke receiving intravenous recombinant tissue-type plasminogen activator therapy: stroke acute management with urgent risk-factor assessment and improvement (SAMURAI) rt-PA registry. Stroke. 2011;42:2196–200.PubMed Nezu T, Koga M, Nakagawara J, Shiokawa Y, Yamagami H, Furui E, Kimura K, Hasegawa Y, Okada Y, Okuda S, Kario K, Naganuma M, Maeda K, Minematsu K, Toyoda K. Early ischemic change on CT versus diffusion-weighted imaging for patients with stroke receiving intravenous recombinant tissue-type plasminogen activator therapy: stroke acute management with urgent risk-factor assessment and improvement (SAMURAI) rt-PA registry. Stroke. 2011;42:2196–200.PubMed

Zurück zum Zitat Schröder J, Cheng B, Ebinger M, Köhrmann M, Wu O, Kang DW, Liebeskind DS, Tourdias T, Singer OC, Christensen S, Campbell B, Luby M, Warach S, Fiehler J, Fiebach JB, Gerloff C, Thomalla G; STIR and VISTA Imaging Investigators. Validity of acute stroke lesion volume estimation by diffusion-weighted imaging-Alberta Stroke Program Early Computed Tomographic Score depends on lesion location in 496 patients with middle cerebral artery stroke. Stroke. 2014;45:3583–8.PubMedPubMedCentral Schröder J, Cheng B, Ebinger M, Köhrmann M, Wu O, Kang DW, Liebeskind DS, Tourdias T, Singer OC, Christensen S, Campbell B, Luby M, Warach S, Fiehler J, Fiebach JB, Gerloff C, Thomalla G; STIR and VISTA Imaging Investigators. Validity of acute stroke lesion volume estimation by diffusion-weighted imaging-Alberta Stroke Program Early Computed Tomographic Score depends on lesion location in 496 patients with middle cerebral artery stroke. Stroke. 2014;45:3583–8.PubMedPubMedCentral

Zurück zum Zitat Albach FN, Brunecker P, Usnich T, Villringer K, Ebinger M, Fiebach JB, Nolte CH. Complete early reversal of diffusion-weighted imaging hyperintensities after ischemic stroke is mainly limited to small embolic lesions. Stroke. 2013;44:1043–8.PubMed Albach FN, Brunecker P, Usnich T, Villringer K, Ebinger M, Fiebach JB, Nolte CH. Complete early reversal of diffusion-weighted imaging hyperintensities after ischemic stroke is mainly limited to small embolic lesions. Stroke. 2013;44:1043–8.PubMed

Zurück zum Zitat Tisserand M, Malherbe C, Turc G, Legrand L, Edjlali M, Labeyrie MA, Seners P, Mas JL, Méder JF, Baron JC, Oppenheim C. Is white matter more prone to diffusion lesion reversal after thrombolysis? Stroke. 2014;45:1167–9.PubMed Tisserand M, Malherbe C, Turc G, Legrand L, Edjlali M, Labeyrie MA, Seners P, Mas JL, Méder JF, Baron JC, Oppenheim C. Is white matter more prone to diffusion lesion reversal after thrombolysis? Stroke. 2014;45:1167–9.PubMed

Zurück zum Zitat Soize S, Tisserand M, Charron S, Turc G, Ben Hassen W, Labeyrie MA, Legrand L, Mas JL, Pierot L, Meder JF, Baron JC, Oppenheim C. How sustained is 24-hour diffusion-weighted imaging lesion reversal? Serial magnetic resonance imaging in a patient cohort thrombolyzed within 4.5 hours of stroke onset. Stroke. 2015;46:704–10.PubMed Soize S, Tisserand M, Charron S, Turc G, Ben Hassen W, Labeyrie MA, Legrand L, Mas JL, Pierot L, Meder JF, Baron JC, Oppenheim C. How sustained is 24-hour diffusion-weighted imaging lesion reversal? Serial magnetic resonance imaging in a patient cohort thrombolyzed within 4.5 hours of stroke onset. Stroke. 2015;46:704–10.PubMed

Zurück zum Zitat Labeyrie MA, Turc G, Hess A, Hervo P, Mas JL, Meder JF, Baron JC, Touzé E, Oppenheim C. Diffusion lesion reversal after thrombolysis: a MR correlate of early neurological improvement. Stroke. 2012;43:2986–91.PubMed Labeyrie MA, Turc G, Hess A, Hervo P, Mas JL, Meder JF, Baron JC, Touzé E, Oppenheim C. Diffusion lesion reversal after thrombolysis: a MR correlate of early neurological improvement. Stroke. 2012;43:2986–91.PubMed

Zurück zum Zitat Rangaraju S, Streib C, Aghaebrahim A, Jadhav A, Frankel M, Jovin TG. Relationship Between Lesion Topology and Clinical Outcome in Anterior Circulation Large Vessel Occlusions. Stroke. 2015;46:1787–92.PubMedPubMedCentral Rangaraju S, Streib C, Aghaebrahim A, Jadhav A, Frankel M, Jovin TG. Relationship Between Lesion Topology and Clinical Outcome in Anterior Circulation Large Vessel Occlusions. Stroke. 2015;46:1787–92.PubMedPubMedCentral

Zurück zum Zitat Payabvash S, Noorbaloochi S, Qureshi AI. Topographic Assessment of Acute Ischemic Changes for Prognostication of Anterior Circulation Stroke. J Neuroimaging. 2017;27:227–31.PubMed Payabvash S, Noorbaloochi S, Qureshi AI. Topographic Assessment of Acute Ischemic Changes for Prognostication of Anterior Circulation Stroke. J Neuroimaging. 2017;27:227–31.PubMed

Zurück zum Zitat Etherton MR, Rost NS, Wu O. Infarct topography and functional outcomes. J Cereb Blood Flow Metab. 2018;38:1517–32.PubMed Etherton MR, Rost NS, Wu O. Infarct topography and functional outcomes. J Cereb Blood Flow Metab. 2018;38:1517–32.PubMed

Zurück zum Zitat Kleine JF, Kaesmacher M, Wiestler B, Kaesmacher J. Tissue-Selective Salvage of the White Matter by Successful Endovascular Stroke Therapy. Stroke. 2017;48:2776–83.PubMed Kleine JF, Kaesmacher M, Wiestler B, Kaesmacher J. Tissue-Selective Salvage of the White Matter by Successful Endovascular Stroke Therapy. Stroke. 2017;48:2776–83.PubMed

Zurück zum Zitat Payabvash S, Taleb S, Qureshi AI. Cerebral regions preserved by successful endovascular recanalization of acute M1 segment occlusions: a voxel based analysis. Br J Radiol. 2017;90:20160869.PubMedPubMedCentral Payabvash S, Taleb S, Qureshi AI. Cerebral regions preserved by successful endovascular recanalization of acute M1 segment occlusions: a voxel based analysis. Br J Radiol. 2017;90:20160869.PubMedPubMedCentral

Zurück zum Zitat Falcao AL, Reutens DC, Markus R, Koga M, Read SJ, Tochon-Danguy H, Sachinidis J, Howells DW, Donnan GA. The resistance to ischemia of white and gray matter after stroke. Ann Neurol. 2004;56:695–701.PubMed Falcao AL, Reutens DC, Markus R, Koga M, Read SJ, Tochon-Danguy H, Sachinidis J, Howells DW, Donnan GA. The resistance to ischemia of white and gray matter after stroke. Ann Neurol. 2004;56:695–701.PubMed

Zurück zum Zitat Arakawa S, Wright PM, Koga M, Phan TG, Reutens DC, Lim I, Gunawan MR, Ma H, Perera N, Ly J, Zavala J, Fitt G, Donnan GA. Ischemic thresholds for gray and white matter: a diffusion and perfusion magnetic resonance study. Stroke. 2006;37:1211–6.PubMed Arakawa S, Wright PM, Koga M, Phan TG, Reutens DC, Lim I, Gunawan MR, Ma H, Perera N, Ly J, Zavala J, Fitt G, Donnan GA. Ischemic thresholds for gray and white matter: a diffusion and perfusion magnetic resonance study. Stroke. 2006;37:1211–6.PubMed

Zurück zum Zitat Diestro JDB, Dmytriw AA, Broocks G, Chen K, Hirsch JA, Kemmling A, Phan K, Bharatha A. Endovascular Thrombectomy for Low ASPECTS Large Vessel Occlusion Ischemic Stroke: A Systematic Review and Meta-Analysis. Can J Neurol Sci. 2020;47:612–9.PubMed Diestro JDB, Dmytriw AA, Broocks G, Chen K, Hirsch JA, Kemmling A, Phan K, Bharatha A. Endovascular Thrombectomy for Low ASPECTS Large Vessel Occlusion Ischemic Stroke: A Systematic Review and Meta-Analysis. Can J Neurol Sci. 2020;47:612–9.PubMed

Zurück zum Zitat Deutschmann H, Hinteregger N, Wießpeiner U, Kneihsl M, Fandler-Höfler S, Michenthaler M, Enzinger C, Hassler E, Leber S, Reishofer G. Automated MRI perfusion-diffusion mismatch estimation may be significantly different in individual patients when using different software packages. Eur Radiol. 2021;31:658–65.PubMed Deutschmann H, Hinteregger N, Wießpeiner U, Kneihsl M, Fandler-Höfler S, Michenthaler M, Enzinger C, Hassler E, Leber S, Reishofer G. Automated MRI perfusion-diffusion mismatch estimation may be significantly different in individual patients when using different software packages. Eur Radiol. 2021;31:658–65.PubMed

Zurück zum Zitat Lansberg MG, Straka M, Kemp S, Mlynash M, Wechsler LR, Jovin TG, Wilder MJ, Lutsep HL, Czartoski TJ, Bernstein RA, Chang CW, Warach S, Fazekas F, Inoue M, Tipirneni A, Hamilton SA, Zaharchuk G, Marks MP, Bammer R, Albers GW; DEFUSE 2 study investigators. MRI profile and response to endovascular reperfusion after stroke (DEFUSE 2): a prospective cohort study. Lancet Neurol. 2012;11:860–7.PubMedPubMedCentral Lansberg MG, Straka M, Kemp S, Mlynash M, Wechsler LR, Jovin TG, Wilder MJ, Lutsep HL, Czartoski TJ, Bernstein RA, Chang CW, Warach S, Fazekas F, Inoue M, Tipirneni A, Hamilton SA, Zaharchuk G, Marks MP, Bammer R, Albers GW; DEFUSE 2 study investigators. MRI profile and response to endovascular reperfusion after stroke (DEFUSE 2): a prospective cohort study. Lancet Neurol. 2012;11:860–7.PubMedPubMedCentral

Zurück zum Zitat Campbell BC, Yassi N, Ma H, Sharma G, Salinas S, Churilov L, Meretoja A, Parsons MW, Desmond PM, Lansberg MG, Donnan GA, Davis SM. Imaging selection in ischemic stroke: feasibility of automated CT-perfusion analysis. Int J Stroke. 2015;10:51–4.PubMed Campbell BC, Yassi N, Ma H, Sharma G, Salinas S, Churilov L, Meretoja A, Parsons MW, Desmond PM, Lansberg MG, Donnan GA, Davis SM. Imaging selection in ischemic stroke: feasibility of automated CT-perfusion analysis. Int J Stroke. 2015;10:51–4.PubMed

Zurück zum Zitat Albers GW, Goyal M, Jahan R, Bonafe A, Diener HC, Levy EI, Pereira VM, Cognard C, Cohen DJ, Hacke W, Jansen O, Jovin TG, Mattle HP, Nogueira RG, Siddiqui AH, Yavagal DR, Baxter BW, Devlin TG, Lopes DK, Reddy VK, de Rochemont Rdu M, Singer OC, Bammer R, Saver JL. Ischemic core and hypoperfusion volumes predict infarct size in SWIFT PRIME. Ann Neurol. 2016;79:76–89.PubMed Albers GW, Goyal M, Jahan R, Bonafe A, Diener HC, Levy EI, Pereira VM, Cognard C, Cohen DJ, Hacke W, Jansen O, Jovin TG, Mattle HP, Nogueira RG, Siddiqui AH, Yavagal DR, Baxter BW, Devlin TG, Lopes DK, Reddy VK, de Rochemont Rdu M, Singer OC, Bammer R, Saver JL. Ischemic core and hypoperfusion volumes predict infarct size in SWIFT PRIME. Ann Neurol. 2016;79:76–89.PubMed

Zurück zum Zitat Lansberg MG, Christensen S, Kemp S, Mlynash M, Mishra N, Federau C, Tsai JP, Kim S, Nogueria RG, Jovin T, Devlin TG, Akhtar N, Yavagal DR, Haussen D, Dehkharghani S, Bammer R, Straka M, Zaharchuk G, Marks MP, Albers GW; CT Perfusion to Predict Response to Recanalization in Ischemic Stroke Project (CRISP) Investigators. Computed tomographic perfusion to Predict Response to Recanalization in ischemic stroke. Ann Neurol. 2017;81:849–56.PubMedPubMedCentral Lansberg MG, Christensen S, Kemp S, Mlynash M, Mishra N, Federau C, Tsai JP, Kim S, Nogueria RG, Jovin T, Devlin TG, Akhtar N, Yavagal DR, Haussen D, Dehkharghani S, Bammer R, Straka M, Zaharchuk G, Marks MP, Albers GW; CT Perfusion to Predict Response to Recanalization in Ischemic Stroke Project (CRISP) Investigators. Computed tomographic perfusion to Predict Response to Recanalization in ischemic stroke. Ann Neurol. 2017;81:849–56.PubMedPubMedCentral