Background
Methods
Subjects
CMR
Ventricular volumes and tricuspid regurgitation
Strain
Dyssynchrony
Cardiopulmonary exercise testing
Statistics
Results
Subjects
Preoperative | Postoperative | P-value | |
---|---|---|---|
Age at CMR (years) | 16 (5–41) | 19 (8–42) | < 0.001 |
Body surface area (m2) | 1.5 ± 0.4 | 1.7 ± 0.3 | 0.002 |
Systolic blood pressure (mm Hg) | 113 ± 17 | 116 ± 11 | 0.39 |
Diastolic blood pressure (mm Hg) | 71 ± 15 | 68 ± 8 | 0.31 |
Heart rate (bpm) | 86 ± 13 | 84 ± 17 | 0.56 |
QRS duration (msec) | 115 ± 24 | 137 ± 24 | < 0.001 |
Ventricular volumes, mass, and ejection fraction
Preoperative | Postoperative | P-value | |
---|---|---|---|
TR fraction (%) | 56 ± 19 | 5 ± 4 | < 0.001 |
Right ventricle | |||
End-diastolic volume (ml/m2) | 242 ± 110 | 137 ± 82 | < 0.001 |
End-systolic volume (ml/m2) | 141 ± 80 | 86 ± 65 | 0.001 |
Stroke volume (ml/m2) | 101 ± 35 | 51 ± 7 | < 0.001 |
Mass (g/m2) | 36 ± 15 | 29 ± 12 | 0.002 |
Ejection fraction (%) | 43 ± 9 | 41 ± 9 | 0.13 |
Left ventricle | |||
End-diastolic volume (ml/m2) | 68 ± 13 | 85 ± 13 | < 0.001 |
End-systolic volume (ml/m2) | 31 ± 8 | 37 ± 10 | 0.001 |
Stroke volume (ml/m2) | 37 ± 8 | 48 ± 6 | < 0.001 |
Mass (g/m2) | 45 ± 10 | 52 ± 8 | < 0.001 |
Ejection fraction (%) | 55 ± 7 | 57 ± 6 | 0.35 |
Left ventricular strain
Preoperative | Postoperative | P-value | |
---|---|---|---|
Global longitudinal strain (%) | 20 ± 3 | 19 ± 4 | 0.12 |
Circumferential strain (%) | |||
Global | 26 ± 4 | 27 ± 3 | 0.45 |
Septum | 22 ± 5 | 25 ± 3 | 0.03 |
Anterior | 27 ± 4 | 27 ± 3 | 0.95 |
Inferior | 29 ± 4 | 29 ± 4 | 0.62 |
Dyssynchrony index (msec) | 32 ± 17 | 21 ± 9 | 0.02 |
Dyssynchrony index (msec) ÷ √RR (sec) | 38 ± 20 | 23 ± 10 | 0.01 |
Left ventricular dyssynchrony
Cardiopulmonary exercise testing
Preoperative | Postoperative | P-value | |
---|---|---|---|
Age (years) | 16 (7–42) | 17 (9–42) | < 0.001 |
BMI (kg/m2) | 21 ± 5 | 21 ± 9 | 0.87 |
Maximum oxygen consumption (% predicted) | 77 ± 16 | 81 ± 14 | 0.44 |
Oxygen pulse (% predicted) | 84 ± 17 | 87 ± 23 | 0.67 |
VE/VCO2 slope | 30 ± 5 | 28 ± 4 | 0.35 |
RER | 1.2 ± 0.1 | 1.2 ± 0.1 | 0.09 |
Peak heart rate (% predicted) | 92 ± 10 | 89 ± 12 | 0.47 |