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Oral Radiology

Erschienen in:

20.07.2022 | Original Article

Evaluation of bone changes on dental panoramic radiography using mandibular indexes and fractal dimension analysis in children with familial Mediterranean fever

verfasst von: Nihal Altunok Ünlü, Alem Coşgun, Halenur Altan

Erschienen in: Oral Radiology | Ausgabe 2/2023

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Abstract

Aim

It was aimed to evaluate the bone microarchitecture of children with FMF in the city of Tokat, where the disease is highly prevalent, in Turkey, one of the countries where familial Mediterranean Fever (FMF) disease is the most common, using mandibular indexes and fractal dimension analysis on panoramic radiography.

Methods

In this retrospective study, the results were evaluated and compared using the mandibular cortical index (MCI), the mental index (MI), the panoramic mandibular index (PMI), and the fractal dimension analysis of six different regions (condyle, angulus, and interdental) on dental panoramic radiographs in 124 children with FMF and 124 healthy children. The data were analyzed using the IBM SPSS V23.

Results

The distribution of MCI in children with FMF was similar to the control group (p > 0.05). The mean MI (3.59) values in FMF patients were statistically higher than the control group (p = 0.016). No statistically significant difference was found in PMI between the patients with FMF and the control group (p > 0.05). No statistically significant difference was found between the mean fractal dimension (FD) values according to the groups (p > 0.05).

Conclusion

Trabecular bone microarchitecture of children with FMF is similar to healthy children. There is no correlation between the duration of colchicine use and bone microarchitecture.

Yildirim K, Karatay S, Cetinkaya R, Uzkeser H, Erdal A, Capoglu I, Erdem FH. Bone mineral density in patients with familial Mediterranean fever. Rheumatol Int. 2009;30(3):305–8.PubMedCrossRef

Kastner DL. Familial Mediterranean fever: the genetics of inflammation. Hosp Pract. 1998;33(4):131–58.CrossRef

Ozen S, Bilginer Y. A clinical guide to autoinflammatory diseases: familial Mediterranean fever and next-of-kin. Nat Rev Rheumatol. 2014;10(3):135–47.PubMedCrossRef

Ben-Chetrit E, Touitou I. Familial Mediterranean fever in the world. Arthritis Rheum. 2009;61(10):1447–53.PubMedCrossRef

Onen F, Sumer H, Tunca M, Ozdogan H. Increased frequency of familial Mediterranean fever in Central Anatolia, Turkey. Clin Exp Rheumatol. 2004;22:31–3.

Livneh A, Langevitz P, Zemer D, Padeh S, Migdal A, Pras M. The changing face of familial Mediterranean fever. Semin Arthritis Rheum. 1996;26(3):612–27.PubMedCrossRef

Aksentijevich I, Centola M, Deng Z, Sood R, Balow J, et al. Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial mediterranean fever. Cell. 1997;90(4):797–807.CrossRef

Cantarini L, Rigante D, Brizi MG, Lucherini OM, Sebastiani GD, Vitale A, Gianneramo V, Galeazzi M. Clinical and biochemical landmarks in systemic autoinflammatory diseases. Ann Med. 2012;44(7):664–73.PubMedCrossRef

Shohat M. Familial Mediterranean Fever. GeneReviews®. 2016.

10.

Yuksel S, Samli H, Colbay M, Dundar U, Acarturk G, et al. Increased Serum osteoprotegerin levels associated with decreased bone mineral density in familial Mediterranean fever. Tohoku J Exp Med. 2009;217(4):321–7.PubMedCrossRef

11.

Bayram M, Yildirim M, Köse A, Seymen F. Pedodonti Anadilim Dalı’nda Başlangıç Muayenesinde Alınan Panoramik Radyografilerin Değerlendirilmesi. İstanbul Üniversitesi Dis Hekimligi Fakültesi Dergisi. 2011;45(3):41–7.

12.

Gümüşsoy İ. Panoramik Radyografilerde Fraktal Analiz Metodunun Uygulanması ve Değişik Röntgen Cihazlarının Fraktal Boyut Değerine Etkisi. Sakarya Med J. 2019;9(3):492–8.CrossRef

13.

White SC, Rudolph DJ. Alterations of the trabecular pattern of the jaws in patients with osteoporosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999;88(5):628–35.PubMedCrossRef

14.

Bayrak S, Göller Bulut D, Orhan K, Sinanoğlu EA, Kurşun Çakmak EŞ, Mısırlı M, Ankaralı H. Evaluation of osseous changes in dental panoramic radiography of thalassemia patients using mandibular indexes and fractal size analysis. Oral Radiol. 2020;36(1):18–24.PubMedCrossRef

15.

Demirbaş AK, Ergün S, Güneri P, Aktener BO, Boyacioǧlu H. Mandibular bone changes in sickle cell anemia: fractal analysis. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol. 2008;106(1):e41–8.CrossRef

16.

Gumussoy I, Miloglu O, Cankaya E, Bayrakdar IS. Fractal properties of the trabecular pattern of the mandible in chronic renal failure. Dentomaxillofac Radiol. 2016;45(5).

17.

Demiralp KÖ, Kurşun-Çakmak EŞ, Bayrak S, Akbulut N, Atakan C, Orhan K. Trabecular structure designation using fractal analysis technique on panoramic radiographs of patients with bisphosphonate intake: a preliminary study. Oral Radiol. 2019;35(1):23–8.PubMedCrossRef

18.

Göller Bulut D, Bayrak S, Uyeturk U, Ankarali H. Mandibular indexes and fractal properties on the panoramic radiographs of the patients using aromatase inhibitors. Br J Radiol. 2018;91(1091):20180442.PubMedPubMedCentralCrossRef

19.

Aktuna Belgin C, Serindere G. Fractal and radiomorphometric analysis of mandibular bone changes in patients undergoing intravenous corticosteroid therapy. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020;130(1):110–5.PubMedCrossRef

20.

Coşgunarslan A, Aşantoğrol F, Soydan Çabuk D, Canger EM. The effect of selective serotonin reuptake inhibitors on the human mandible. Oral Radiol. 2020;37(1):20–8.PubMedCrossRef

21.

Hastar E, Yilmaz HH, Orhan H. Evaluation of mental index, mandibular cortical index and panoramic mandibular index on dental panoramic radiographs in the elderly. Eur J Dent. 2019;05(01):060–7.

22.

Kwon AY, Huh KH, Yi WJ, Lee SS, Choi SC, Heo MS. Is the panoramic mandibular index useful for bone quality evaluation? Imaging Sci Dent. 2017;47(2):87–92.PubMedPubMedCentralCrossRef

23.

Baker-LePain JC, Lane NE. Role of bone architecture and anatomy in osteoarthritis. Bone. 2012;51(2):197–203.PubMedPubMedCentralCrossRef

24.

Bollen AM, Taguchi A, Hujoel PP, Hollender LG. Fractal dimension on dental radiographs. Dentomaxillofac Radiol. 2001;30(5):270–5.PubMedCrossRef

25.

Lopes R, Betrouni N. Fractal and multifractal analysis: a review. Med Image Anal. 2009;13(4):634–49.PubMedCrossRef

26.

Apolinário AC, Sindeaux R, De Souza Figueiredo PT, Guimarães ATB, Acevedo AC, et al. Dental panoramic indices and fractal dimension measurements in osteogenesis imperfecta children under pamidronate treatment. Dentomaxillofac Radiol. 2016;45(4):20150400.PubMedPubMedCentralCrossRef

27.

Klemetti E, Kolmakov S, Kröger H. Pantomography in assessment of the osteoporosis risk group. Eur J Oral Sci. 1994;102(1):68–72.CrossRef

28.

Ledgerton D, Horner K, Devlin H, Worthington H. Radiomorphometric indices of the mandible in a British female population. Dentomaxillofac Radiol. 1999;28(3):173–81.PubMedCrossRef

29.

Benson BW, Prihoda TJ, Glass BJ. Variations in adult cortical bone mass as measured by a panoramic mandibular index. Oral Surg Oral Med Oral Pathol. 1991;71(3):349–56.PubMedCrossRef

30.

Koo TK, Li MY. A guideline of selecting and reporting intraclass correlation coefficients for reliability research. J Chiropr Med. 2016;15(2):155–63.PubMedPubMedCentralCrossRef

31.

Alonso MBC, Cortes AR, Camargo AJ, Arita ES, Haiter-Neto F, Watanabe PCA. Assessment of panoramic radiomorphometric ındices of the mandible in a brazilian population. Int Sch Res Netw ISRN Rheumatol. 2011.

32.

Gulsahi A, Yüzügüllü B, İmirzalıoğlu P, Genç Y. Assessment of panoramic radiomorphometric indices in Turkish patients of different age groups, gender and dental status. Dentomaxillofac Radiol. 2008;37(5):288–92.PubMedCrossRef

33.

Frascino AV, Costa C, Salgado DMRA, Coracin FL, Fava M, Odone-Filho V. Mandibular radiomorphometric assessment of bone mineral density in survivors of pediatric hematopoietic stem-cell transplantation. Clinics. 2019;74:e929.PubMedPubMedCentralCrossRef

34.

Nakamoto T, Taguchi A, Ohtsuka M, Suei Y, Fujita M, et al. Dental panoramic radiograph as a tool to detect postmenopausal women with low bone mineral density: untrained general dental practitioners’ diagnostic performance. Osteoporos Int. 2003;14(8):659–64.PubMedCrossRef

35.

Govindraju P, Chandra P. Radiomorphometric indices of the mandible—an indicator of osteoporosis. J Clin Diagn Res JCDR. 2014;8(3):195.PubMed

36.

Firman RN, Sufiawati I, Primarti RS, Nurrachman AS, Damayanti MA. Mandıbular bone quality of panoramic radiographs in HIV-infected children. Dentino Jurnal Kedokteran Gigi. 2020;5(1):85–9.CrossRef

37.

Taguchi A, Suei Y, Horner K, Devlin H, Nakamoto T, et al. Is there any difference between the British and Japanese definitions of the mandibular cortical index (MCI) on panoramic radiographs? A pilot study. Oral Radiol. 2004;20(1):44–8.CrossRef

38.

Taguchi A. Triage screening for osteoporosis in dental clinics using panoramic radiographs. Oral Dis. 2010;16(4):316–27.PubMedCrossRef

39.

Yaşar F, Akgünlü F. The differences in panoramic mandibular indices and fractal dimension between patients with and without spinal osteoporosis. Dentomaxillofac Radiol. 2006;35(1):1–9.PubMedCrossRef

40.

Caligiuri P, Giger ML, Favus M. Multifractal radiographic analysis of osteoporosis. Med Phys. 1994;21(4):503–8.PubMedCrossRef

41.

Ohya K. Effects of colchicine on osteoblast in rat: an ultrastructural study. Bull Tokyo Med Dental Univ. 1978;25(4):277–95.

42.

Oda T. Effect of colchicine on the Golgi apparatus and the lysosomal system in osteoclasts. Jpn J Oral Biol. 1990;32(4):422–39.CrossRef

43.

Koşan C, Sepetçigil O, Çayır A, Kaya A, Özkan B. Ailevi Akdeniz Ateşi Olan Çocuklarda Kemik Metabolizmasının Değerlendirilmesi. Turk J Pediatric Dis. 2012;6(3):139–45.

44.

Aral CA, Aral K, Yay A, Özçoban Ö, Berdeli A, Saraymen R. Effects of colchicine on gingival inflammation, apoptosis, and alveolar bone loss in experimental periodontitis. J Periodontol. 2018;89(5):577–85.PubMedCrossRef

Titel: Evaluation of bone changes on dental panoramic radiography using mandibular indexes and fractal dimension analysis in children with familial Mediterranean fever
verfasst von: Nihal Altunok Ünlü
Alem Coşgun
Halenur Altan
Publikationsdatum: 20.07.2022
Verlag: Springer Nature Singapore
Erschienen in: Oral Radiology / Ausgabe 2/2023
Print ISSN: 0911-6028
Elektronische ISSN: 1613-9674
DOI: https://doi.org/10.1007/s11282-022-00639-6

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Evaluation of bone changes on dental panoramic radiography using mandibular indexes and fractal dimension analysis in children with familial Mediterranean fever

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