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01.12.2024 | Case Report

Can photobiomodulation be an antidote to botulinum toxin?

verfasst von: Elen de Souza Tolentino, Camila Camarini, Giovana Felipe Hara, Fernanda Vessoni Iwaki, Aline Thomazelli Peres Tomazoli

Erschienen in: Lasers in Dental Science | Ausgabe 1/2024

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Abstract

Purpose

Although botulinum toxin (BT) is a safe and well-established method for chemoimmobilization of facial muscles, undesired results can occur. The reversal of the effects of BT is poorly documented in the literature. This work describes how photobiomodulation (PBM) was used to reverse unwanted results from the application of BT to the lower face in a patient with aesthetic and functional complaints (asymmetry, difficulty speaking, whistling, eating, and controlling saliva).

Methods

PBM (808 nm, 100mW, 0.35 W/cm², 10.7 J/cm2) was performed on the upper and lower labial muscles and chin to reverse the BT applied 14 days ago. Irradiation was performed at each point with the laser tip in contact with the skin for 30 s at each point (3 J), totaling 72 J per session (20 points).

Results

After two sessions (one-week interval) of PBM, there was an improvement in lip movements, with restored function.

Conclusion

In the parameters used, PBM was able to reverse the effects of BT on the lower face.

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Titel: Can photobiomodulation be an antidote to botulinum toxin?
verfasst von: Elen de Souza Tolentino
Camila Camarini
Giovana Felipe Hara
Fernanda Vessoni Iwaki
Aline Thomazelli Peres Tomazoli
Publikationsdatum: 01.12.2024
Verlag: Springer International Publishing
Erschienen in: Lasers in Dental Science / Ausgabe 1/2024
Elektronische ISSN: 2367-2587
DOI: https://doi.org/10.1007/s41547-024-00214-8

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Can photobiomodulation be an antidote to botulinum toxin?