Background
Material and method
Results
Clinical manifestation | Clinical manifestation | ||||
---|---|---|---|---|---|
Age at presentation (months) mean ± SD | 33 ± 39 months (range 20 - 178) | MRI findings | Absence of septum pellucidum(%) | 62 | |
Ht SDS, mean ± SD | -0.97 ± 1.97 | Pituitary hypoplasia (%) | 33 | ||
Wt SDS, mean ± SD | 0.02 ± 2.35 | Abnormal of corpus callosum (%) | 16 | ||
Eye presentation | Nystagmus (%) | 54 | Cortical dysplasia (%) | 8 | |
Squint (%) | 3 | Endocrine abnormalities | Hypothyroid (%) | 35 | |
Poor vision (%) | 35 | GH insufficiency (%) | 29 | ||
Delayed development (%) | 16.2 | Delayed/arrested puberty/suspected HG (%) | 23 | ||
Seizure (%) | 7.9 | Cortical insufficiency (%) | 17 | ||
Hypoglycemia (%) | 8.1 | Diabetes insipidus (%) | 19 | ||
Neonatal jaundice (%) | 2.7 | Eye examination | Unilat ON hypoplasia | 13 | |
Undescended testes (%) (boys) | 5.4 | Bilat ON hypoplasia | 84 | ||
Micropenis (%) (boys) | 21 | Microcornea | 3 |